Produções Científicas
01 de abril 2021
An explorative analysis of the differences in levels of happiness between cancer patients, informal caregivers and the general population
Background: Although cancer patients experience distressing symptoms and health-related changes in their quality of life, they may report positive emotional states. The lives of informal caregivers of cancer patients may also be affected by the patient’s cancer diagnosis; however, they may also find benefits in their experiences. Noticeable changes are reported in personal priorities after an oncologic diagnosis that can lead individuals to restructure their values and the way they perceive life. This study aims to assess happiness/satisfaction with life...
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01 de abril 2021
A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis
Despite much effort to improve treatments, patients with malignant glioma still present a very poor prognosis that has not changed significantly in the last decades. In this context, it is crucial to better understand glioma pathogenesis to identify new molecular prognostic subgroups and therapeutic targets. WNT6 was recently identified as a new oncogenic molecule in glioblastoma (GBM), with prognostic value in patients, but the mechanisms underlying WNT6 aberrant expression in glioma are still unknown. WNT6 was overexpressed in a subset...
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01 de abril 2021
A multinational review: Oesophageal cancer in low to middle‑income countries (Review)
Oesophageal cancer (OC) is an aggressive neoplasm that manifests in the gastrointestinal tract and is the result of numerous factors that can contribute to the development of the disease. These may include old age, nutritional deficien‑ cies, oesophageal obstruction and food ingestion difficulties. Environmental factors serve a large role in increasing the risk of developing OC. Two factors that serve an increasing risk of developing OC are the use of tobacco and the consumption of alcohol. Genetic factors also exhibit...
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01 de abril 2021
A 30-Year Long-Term Experience in Appendix Neuroendocrine Neoplasms—Granting a Positive Outcome
Neuroendocrine neoplasms (NENs) are the most common tumor of the appendix and have an excellent prognosis. Appendiceal tumors diagnosed between 1989 and 2019 were reviewed, and clinical data were collected from patient files. Part of the series was immuno-profiled for markers related to cell cycle proliferation and/or senescence-type, apoptotic, and metastatic potential. Appendix NENs were detected in 74 patients, with 0.47% of incidence per appendectomy. The median age of the patients was 21.5 years, with two age peaks of incidence...
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Artigos mais lidos
Artigos mais lidos
Adherence
Adolescent Barrier
Questionnaire
Barriers
Psychometry
Brazil
Cancer
homologous recombination deficiency
copy number alterations
inflammatory breast cancer
microarray
gene variants
genomic scars
BRCAX
breast cancer predisposition
whole‐exome sequencing
hereditary breast and ovarian cancer predisposition syndrome
hereditary cancer
Pesquisa
Artigos mais lidos
Artigos mais lidos
Adherence
Adolescent Barrier
Questionnaire
Barriers
Psychometry
Brazil
Cancer
homologous recombination deficiency
copy number alterations
inflammatory breast cancer
microarray
gene variants
genomic scars
BRCAX
breast cancer predisposition
whole‐exome sequencing
hereditary breast and ovarian cancer predisposition syndrome
hereditary cancer