Publicações Científicas 2021

1. Causin RL, Freitas AJA, Trovo Hidalgo Filho CM, Reis RD, Reis RM, Marques MMC. A Systematic Review of MicroRNAs Involved in Cervical Cancer Progression. Cells. 2021;10(3). doi: 10.3390/cells10030668


2. Melani AGF, Romagnolo LGC, Davila EP. Safe Introduction of New Technologies and Techniques in Minimally Invasive Colorectal Surgery. Clin Colon Rectal Surg. 2021;34(3):181-5. doi: 10.1055/s-0040-1722764


3. Secolin R, de Araujo TK, Gonsales MC, Rocha CS, Naslavsky M, Marco L, et al. Genetic variability in COVID-19-related genes in the Brazilian population. Hum Genome Var. 2021;8(1):15. doi: 10.1038/s41439-021-00146-w


4. Eskelinen M, Meklin J, Syrjänen K, Eskelinen M. A Diagnostic Score for Acute Small Bowel Obstruction. Anticancer Res. 2021;41(4):1959-70. doi: 10.21873/anticanres.14963


5. Secolin R, Gonsales MC, Rocha CS, Naslavsky M, De Marco L, Bicalho MAC, et al. Exploring a Region on Chromosome 8p23.1 Displaying Positive Selection Signals in Brazilian Admixed Populations: Additional Insights Into Predisposition to Obesity and Related Disorders. Front Genet. 2021;12:636542. doi: 10.3389/fgene.2021.636542


6. Giaccherini M, Macauda A, Orciuolo E, Rymko M, Gruenpeter K, Dumontet C, et al. Genetically determined telomere length and multiple myeloma risk and outcome. Blood Cancer J. 2021;11(4):74. doi: 10.1038/s41408-021-00462-y


7. Dezen T, Rossini RR, Spadin MD, Da Cunha Andrade CEM, Schimidt R, Vieira MA, et al. Accuracy of MRI for diagnosing pelvic and para‑aortic lymph node metastasis in cervical cancer. Oncol Rep. 2021;45(6). doi: 10.3892/or.2021.8051


8. Silva Junior JM, Katayama HT, Lopes FMV, Toledo DO, Amendola CP, Oliveira FDS, et al. Referral to immediate post-operative care in an intensive care unit from the perspective of anesthesiologists, surgeons, and intensive care physicians: a cross-sectional questionnaire. Braz J Anesthesiol. 2021. doi: 10.1016/j.bjane.2021.03.025


9. de Lima C, Fidelesdos Santos Neto M, Costa RFA, Franco JO, Calfi GS, Paiva BSR, et al. Characteristics of palliative care publications by South American authors in the last 20 years: Systematic literature review with bibliometric analysis. J Pain Symptom Manage. 2021. doi: 10.1016/j.jpainsymman.2021.03.017


10. Hunt B, Fregnani J, Brenes D, Schwarz RA, Salcedo MP, Possati-Resende JC, et al. Cervical lesion assessment using real-time microendoscopy image analysis in Brazil: The CLARA study. Int J Cancer. 2021. doi: 10.1002/ijc.33543


11. Zito Marino F, Sabetta R, Pagliuca F, Brunelli M, Aquino G, Perdonà S, et al. Discrepancy of p16 immunohistochemical expression and HPV RNA in penile cancer. A multiplex in situ hybridization/immunohistochemistry approach study. Infect Agent Cancer. 2021;16(1):22. doi: 10.1186/s13027-021-00361-8


12. Eskelinen M, Meklin J, Syrjänen K, Eskelinen M. A Diagnostic Score (DS) Is a Powerful Tool in Diagnosis of Acute Appendicitis in Elderly Patients With Acute Abdominal Pain. Anticancer Res. 2021;41(3):1459-69. doi: 10.21873/anticanres.14904


13. de Lima C, Paiva BSR, Dos Santos Neto MF, Hui D, Perez-Cruz PE, Zimmermann C, et al. The Impact of International Research Collaborations on the Citation Metrics and the Scientific Potential of South American Palliative Care Research: Bibliometric Analysis. Ann Glob Health. 2021;87(1):32. doi: 10.5334/aogh.3158


14. Mazzutti FS, Custódio IDD, Lima MTM, Carvalho KP, Pereira TSS, Molina M, et al. Breast Cancer Survivors Undergoing Endocrine Therapy Have a Worrying Risk Factor Profile for Cardiovascular Diseases. Nutrients. 2021;13(4). doi: 10.3390/nu13041114


15. Pellizoni FP, Leite AZ, Rodrigues NC, Ubaiz MJ, Gonzaga MI, Takaoka NNC, et al. Detection of Dysbiosis and Increased Intestinal Permeability in Brazilian Patients with Relapsing-Remitting Multiple Sclerosis. Int J Environ Res Public Health. 2021;18(9). doi: 10.3390/ijerph18094621


16. Rosa MN, LRV ES, Longato GB, Evangelista AF, Gomes INF, Alves ALV, et al. Bioprospecting of Natural Compounds from Brazilian Cerrado Biome Plants in Human Cervical Cancer Cell Lines. Int J Mol Sci. 2021;22(7). doi: 10.3390/ijms22073383


17. Nobrega de Almeida J, Francisco EC, Holguín Ruiz A, Cuéllar LE, Rodrigues Aquino V, Verena Mendes A, et al. Epidemiology, clinical aspects, outcomes and prognostic factors associated with Trichosporon fungaemia: results of an international multicentre study carried out at 23 medical centres. J Antimicrob Chemother. 2021. doi: 10.1093/jac/dkab085


18. Kuasne H, Canto LMD, Aagaard MM, Muñoz JJM, Jamblinne C, Marchi FA, et al. Penile Cancer-Derived Cells Molecularly Characterized as Models to Guide Targeted Therapies. Cells. 2021;10(4). doi: 10.3390/cells10040814


19. Vieira de Castro J, C SG, E PM, Miranda-Lorenzo I, M TC, Longatto-Filho A, et al. Intracellular Autofluorescence as a New Biomarker for Cancer Stem Cells in Glioblastoma. Cancers (Basel). 2021;13(4). doi: 10.3390/cancers13040828


20. de Paula AE, Galvão HCR, Bonatelli M, Sabato C, Fernandes GC, Berardinelli GN, et al. Clinicopathological and molecular characterization of Brazilian families at risk for Lynch syndrome. Cancer Genet. 2021;254-255:82-91. doi: 10.1016/j.cancergen.2021.02.003


21. Fernandes FG, Silveira HCS, Júnior JNA, da Silveira RA, Zucca LE, Cárcano FM, et al. Somatic Copy Number Alterations and Associated Genes in Clear-Cell Renal-Cell Carcinoma in Brazilian Patients. Int J Mol Sci. 2021;22(5). doi: 10.3390/ijms22052265


22. Baiocchi G, Vieira M, Moretti-Marques R, Mantoan H, Faloppa C, Damasceno RCF, et al. Uterine transposition for gynecological cancers. Int J Gynecol Cancer. 2021;31(3):442-6. doi: 10.1136/ijgc-2020-001780


23. Vieira MA, Vieira AGS, Fonseca DSL, Jorge GE, Lopes LF, Ribeiro RC. Uterine transposition in a pre-pubertal patient. Int J Gynecol Cancer. 2021;31(3):492-3. doi: 10.1136/ijgc-2020-002074


24. Macauda A, Piredda C, Clay-Gilmour AI, Sainz J, Buda G, Markiewicz M, et al. Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients. Int J Cancer. 2021. doi: 10.1002/ijc.33547


25. Lopez A, Rodriguez J, Estrada E, Aragona A, Chavez C, Amaro K, et al. Neoadjuvant chemotherapy in pregnant patients with cervical cancer: a Latin-American multicenter study. Int J Gynecol Cancer. 2021;31(3):468-74. doi: 10.1136/ijgc-2020-001764


26. Alves ALV, Gomes INF, Carloni AC, Rosa MN, da Silva LS, Evangelista AF, et al. Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives. Stem Cell Res Ther. 2021;12(1):206. doi: 10.1186/s13287-021-02231-x


27. Salcedo MP, Varon ML, Phoolcharoen N, Osman N, David E, Rangeiro R, et al. Building local capacity for cervical cancer prevention in low resource settings: Changing strategy during the COVID-19 pandemic. J Glob Health. 2021;11:03044. doi: 10.7189/jogh.11.03044


28. Cayres LCF, de Salis LVV, Rodrigues GSP, Lengert AVH, Biondi APC, Sargentini LDB, et al. Detection of Alterations in the Gut Microbiota and Intestinal Permeability in Patients With Hashimoto Thyroiditis. Front Immunol. 2021;12:579140. doi: 10.3389/fimmu.2021.579140


29. Bonin-Jacob CM, Almeida-Lugo LZ, Puga MAM, Machado AP, Padovani CTJ, Noceti MC, et al. IL-6 and IL-10 in the serum and exfoliated cervical cells of patients infected with high-risk human papillomavirus. PLoS One. 2021;16(3):e0248639. doi: 10.1371/journal.pone.0248639


30. Kuruvilla J, Ramchandren R, Santoro A, Paszkiewicz-Kozik E, Gasiorowski R, Johnson NA, et al. Pembrolizumab versus brentuximab vedotin in relapsed or refractory classical Hodgkin lymphoma (KEYNOTE-204): an interim analysis of a multicentre, randomised, open-label, phase 3 study. Lancet Oncol. 2021;22(4):512-24. doi: 10.1016/s1470-2045(21)00005-x


31. Talukdar FR, Soares Lima SC, Khoueiry R, Laskar RS, Cuenin C, Sorroche BP, et al. Genome-wide DNA methylation profiling of esophageal squamous cell carcinoma from global high-incidence regions identifies crucial genes and potential cancer markers. Cancer Res. 2021. doi: 10.1158/0008-5472.Can-20-3445


32. de Oliveira Cavagna R, Leal LF, de Paula FE, Bernardinelli GN, Reis RM. A PCR-Based Approach for Driver Mutation Analysis of EGFR, KRAS, and BRAF Genes in Lung Cancer Tissue Sections. Methods Mol Biol. 2021;2279:109-26. doi: 10.1007/978-1-0716-1278-1_9


33. Faustino SES, Tjioe KC, Assao A, Pereira MC, Carvalho AL, Kowalski LP, et al. Association of lymph vessel density with occult lymph node metastasis and prognosis in oral squamous cell carcinoma. BMC Oral Health. 2021;21(1):114. doi: 10.1186/s12903-021-01459-6


34. de Assis Pinheiro J, Freitas FV, Borçoi AR, Mendes SO, Conti CL, Arpini JK, et al. Alcohol consumption, depression, overweight and cortisol levels as determining factors for NR3C1 gene methylation. Sci Rep. 2021;11(1):6768. doi: 10.1038/s41598-021-86189-z


35. Longatto-Filho A. Microbiota in Cancer Development. Pathobiology. 2021;88(2):115. doi: 10.1159/000512577


36. Ferreira JMM, Cunha P, Carneiro A, Vila I, Cunha C, Silva C, et al. Sarcopenia as a Prognostic Factor in Peripheral Arterial Disease: Descriptive Review. Ann Vasc Surg. 2021. doi: 10.1016/j.avsg.2021.01.076


37. Nshizirungu JP, Bennis S, Mellouki I, Benajah DA, Lahmidani N, El Bouhaddoutti H, et al. Microsatellite Instability Analysis in Gastric Carcinomas of Moroccan Patients. Genet Test Mol Biomarkers. 2021;25(2):116-23. doi: 10.1089/gtmb.2020.0146


38. Oliveira HF, Yoshinari GH, Jr., Veras IM, de Almeida WJ, Jr., Freitas NMA, Castilho MS, et al. Impact of the COVID-19 pandemic on Radiation Oncology Departments in Brazil Impact of COVID-19 on Brazilian Radiotherapy. Adv Radiat Oncol. 2021:100667. doi: 10.1016/j.adro.2021.100667


39. Faria EF, Maciel CVM, Berger A, Mitre A, Dauster B, Freitas CH, Jr., et al. Recommendations on robotic-assisted radical prostatectomy: a Brazilian experts' consensus. J Robot Surg. 2021. doi: 10.1007/s11701-020-01186-0


40. Hui D, Mo L, Paiva CE. The Importance of Prognostication: Impact of Prognostic Predictions, Disclosures, Awareness, and Acceptance on Patient Outcomes. Curr Treat Options Oncol. 2021;22(2):12. doi: 10.1007/s11864-020-00810-3


41. Deadame de Figueiredo Nicolete L, Vladimiro Cunha C, Paulo Tavanez J, Tomazini Pinto M, Strazza Rodrigues E, Kashima S, et al. Hepatitis delta: In vitro evaluation of cytotoxicity and cytokines involved in PEG-IFN therapy. Int Immunopharmacol. 2021;91:107302. doi: 10.1016/j.intimp.2020.107302


42. Eskelinen M, Meklin J, SyrjÄnen K, Eskelinen M. Pediatric Acute Appendicitis Score in Children With Acute Abdominal Pain (AAP). Anticancer Res. 2021;41(1):297-306. doi: 10.21873/anticanres.14776


43. Bragagnoli AC, Araujo RLC, Ferraz MW, Dos Santos LV, Abdalla KC, Comar F, et al. Metformin plus lrinotecan in patients with refractory colorectal cancer: a phase 2 clinical trial. Br J Cancer. 2021;124(6):1072-8. doi: 10.1038/s41416-020-01208-6


44. de Oliveira Faria S, Howell D, Lopes Carvalho A, de Oliveira Faria R, Eluf Neto J. Adherence to intensive nutrition care in head and neck cancer patients undergoing radiotherapy. Eur Arch Otorhinolaryngol. 2021. doi: 10.1007/s00405-020-06550-2


45. Gomes I, Moreno DA, Dos Reis MB, da Silva LS, Leal LF, Gonçalves GM, et al. Low MGMT digital expression is associated with a better outcome of IDH1 wildtype glioblastomas treated with temozolomide. J Neurooncol. 2021;151(2):135-44. doi: 10.1007/s11060-020-03675-6


46. Evangelista AF, Oliveira RJ, VA OS, RA DCV, Reis RM, MM CM. Integrated analysis of mRNA and miRNA profiles revealed the role of miR-193 and miR-210 as potential regulatory biomarkers in different molecular subtypes of breast cancer. BMC Cancer. 2021;21(1):76. doi: 10.1186/s12885-020-07731-2


47. Vieira MA, de Araújo RLC, da Cunha Andrade CEM, Schmidt RL, Filho AL, Reis RD. A randomized clinical trial of a new anti-cervical stenosis device after conization by loop electrosurgical excision. PLoS One. 2021;16(1):e0242067. doi: 10.1371/journal.pone.0242067


48. Paz-Ares L, Ciuleanu TE, Cobo M, Schenker M, Zurawski B, Menezes J, et al. First-line nivolumab plus ipilimumab combined with two cycles of chemotherapy in patients with non-small-cell lung cancer (CheckMate 9LA): an international, randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22(2):198-211. doi: 10.1016/s1470-2045(20)30641-0


49. Mauro GP, Medici CTM, Casimiro LC, Weltman E. Radiotherapy for early and advanced stages Follicular Lymphoma. Clinics (Sao Paulo). 2021;76:e2059. doi: 10.6061/clinics/2021/e2059


50. Fonseca BO, Possati-Resende JC, Salcedo MP, Schmeler KM, Accorsi GS, Fregnani J, et al. Topical Imiquimod for the Treatment of High-Grade Squamous Intraepithelial Lesions of the Cervix: A Randomized Controlled Trial. Obstet Gynecol. 2021;137(6):1043-53. doi: 10.1097/aog.0000000000004384


51. Tukiama R, Vieira RAC, Facina G, da Cunha Leal P, Zucca-Matthes G. Oncologic Safety of Autologous Fat Grafting after Breast Cancer Surgical Treatment: A Matched Cohort Study. Plast Reconstr Surg. 2021. doi: 10.1097/prs.0000000000008037


52. Ferreira CS, Rodrigues J, Moreira S, Ribeiro F, Longatto-Filho A. Breast cancer screening adherence rates and barriers of implementation in ethnic, cultural and religious minorities: A systematic review. Mol Clin Oncol. 2021;15(1):139. doi: 10.3892/mco.2021.2301


53. Michalowski MB, Cecconello DK, Lins MM, Carvalho M, Silva KAS, Cristofani L, et al. Influence of different asparaginase formulations in the prognosis of children with acute lymphocytic leukaemia in Brazil: a multicentre, retrospective controlled study. Br J Haematol. 2021. doi: 10.1111/bjh.17494


54. Borçoi AR, Mendes SO, Moreno IAA, Gasparini Dos Santos J, Freitas FV, Pinheiro JA, et al. Food and nutritional insecurity is associated with depressive symptoms mediated by NR3C1 gene promoter 1F methylation. Stress. 2021:1-8. doi: 10.1080/10253890.2021.1923692


55. Bitencourt AGV, Pires BS, Calsavara VF, Negrão EMS, Souza JA, Graziano L, et al. Prognostic value of response evaluation based on breast MRI after neoadjuvant treatment: a retrospective cohort study. Eur Radiol. 2021. doi: 10.1007/s00330-021-08042-1


56. Ferreira NN, de Oliveira Junior E, Granja S, Boni FI, Ferreira LMB, Cury BSF, et al. Nose-to-brain co-delivery of drugs for glioblastoma treatment using nanostructured system. Int J Pharm. 2021;603:120714. doi: 10.1016/j.ijpharm.2021.120714


57. Pedrão PG, de Carvalho AC, Possati-Resende JC, de Paula Cury F, Campanella NC, de Oliveira CM, et al. DNA Recovery Using Ethanol-Based Liquid Medium from FTA Card-Stored Samples for HPV Detection. Acta Cytol. 2021;65(3):264-71. doi: 10.1159/000515913


58. Hurvitz SA, Saura C, Oliveira M, Trudeau ME, Moy B, Delaloge S, et al. Efficacy of Neratinib Plus Capecitabine in the Subgroup of Patients with Central Nervous System Involvement from the NALA Trial. Oncologist. 2021. doi: 10.1002/onco.13830


59. Franchini Melani AG, Capochin Romagnolo LG. Management of postoperative complications during laparoscopic anterior rectal resection. Minerva Surg. 2021. doi: 10.23736/s2724-5691.21.08890-0


60. Cunha Júnior AD, Bragagnoli AC, Costa FO, Carvalheira JBC. Repurposing metformin for the treatment of gastrointestinal cancer. World J Gastroenterol. 2021;27(17):1883-904. doi: 10.3748/wjg.v27.i17.1883


61. Cavagna R, Escremim de Paula F, Sant'Anna D, Santana I, da Silva VD, da Silva ECA, et al. Frequency of KRAS p.Gly12Cys Mutation in Brazilian Patients With Lung Cancer. JCO Glob Oncol. 2021;7:639-45. doi: 10.1200/go.20.00615


62. Causin RL, da Silva LS, Evangelista AF, Leal LF, Souza KCB, Pessôa-Pereira D, et al. MicroRNA Biomarkers of High-Grade Cervical Intraepithelial Neoplasia in Liquid Biopsy. Biomed Res Int. 2021;2021:6650966. doi: 10.1155/2021/6650966


63. Pinto MT, Cárcano FM, Vieira AGS, Cabral ERM, Lopes LF. Molecular Biology of Pediatric and Adult Male Germ Cell Tumors. Cancers (Basel). 2021;13(10). doi: 10.3390/cancers13102349


64. Bajorin DF, Witjes JA, Gschwend JE, Schenker M, Valderrama BP, Tomita Y, et al. Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma. N Engl J Med. 2021;384(22):2102-14. doi: 10.1056/NEJMoa2034442


65. Lopes RD, de Barros ESPGM, Furtado RHM, Macedo AVS, Bronhara B, Damiani LP, et al. Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial. Lancet. 2021;397(10291):2253-63. doi: 10.1016/s0140-6736(21)01203-4


66. Palhares DMF, Pimentel LCF, Castilho MS, Costa ABD, Reisner ML, Kuhnen FQ, et al. Hypofractionated radiotherapy recommendations for localized prostate cancer in Brasil. Rev Assoc Med Bras (1992). 2021;67(1):7-18. doi: 10.1590/1806-9282.67.01.002


67. de CFC, Dufloth R, de Carvalho AC, Reis RM, Santana I, Carvalho RS, et al. Correlation of p16 immunohistochemistry with clinical and epidemiological features in oropharyngeal squamous-cell carcinoma. PLoS One. 2021;16(6):e0253418. doi: 10.1371/journal.pone.0253418


68. Silva VAO, André ND, Sousa TAE, Alves VM, Kettelhut IDC, De Lucca FL. Nuclear PKR in retinal neurons in the early stage of diabetic retinopathy in streptozotocin‑induced diabetic rats. Mol Med Rep. 2021;24(2). doi: 10.3892/mmr.2021.12253


69. Carvalho RS, Scapulatempo-Neto C, Curado MP, Capuzzo RC, Teixeira FM, Pires RC, et al. HPV-induced oropharyngeal squamous cell carcinomas in Brazil: prevalence, trend, clinical and epidemiological characterization. Cancer Epidemiol Biomarkers Prev. 2021. doi: 10.1158/1055-9965.Epi-21-0016


70. Vieira R, Biller G, Silva F, Silva JJD, Oliveira MA, Bailão-Junior A. New criteria for breast symmetry evaluation after breast conserving surgery for cancer. Rev Col Bras Cir. 2021;48:e20202698. doi: 10.1590/0100-6991e-20202698


71. Santos BDD, Marques-Camargo AR, Pan R, Reis S, Andrade RC, Neris RR, et al. Family knowledge about the legal rights of children and adolescents with cancer. Rev Bras Enferm. 2021;74(6):e20200725. doi: 10.1590/0034-7167-2020-0725


72. Janjigian YY, Shitara K, Moehler M, Garrido M, Salman P, Shen L, et al. First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial. Lancet. 2021. doi: 10.1016/s0140-6736(21)00797-2


73. Beltrame MP, Souto EX, Yamamoto M, Furtado FM, da Costa ES, Sandes AF, et al. Updating recommendations of the Brazilian Group of Flow Cytometry (GBCFLUX) for diagnosis of acute leukemias using four-color flow cytometry panels. Hematol Transfus Cell Ther. 2021. doi: 10.1016/j.htct.2021.04.001


74. Eskelinen M, Meklin J, Syrjänen K, Eskelinen M. A Diagnostic Score for Reliable Confirmation of Acute Renal Colic Among Patients With Acute Abdominal Pain. Anticancer Res. 2021;41(6):3045-54. doi: 10.21873/anticanres.15087


75. Teixeira SA, Viapiano MS, Andrade AF, Nandhu MS, Pezuk JA, Bidinotto LT, et al. The Carbonic Anhydrase Inhibitor E7070 Sensitizes Glioblastoma Cells to Radio- and Chemotherapy and Reduces Tumor Growth. Mol Neurobiol. 2021. doi: 10.1007/s12035-021-02437-3


76. Silva NMF, Carvalho IRA, Lopes LP, Menezes TM, Guandalini VR, Capuzzo RC. Evolution of Nutritional Status in Patients with Advanced Head and Neck Cancer Undergoing Surgical Treatment or Organ Preservation Protocol. Nutr Cancer. 2021:1-8. doi: 10.1080/01635581.2021.1931367


77. Cita RF, Mendes MF, Nogueira DP, Souza TL, Stelet VN. The novel HLA-B*15:554 allele identified in four Brazilian individuals. Hla. 2021;97(2):145-6. doi: 10.1111/tan.14096


78. Stelet VN, Cita RF, Mendes MF, Romero M, Abdelhay E. Identification of the novel HLA-A*01:01:01:53 allele generated by recombination in intron 1. Hla. 2021;97(2):133-4. doi: 10.1111/tan.14093


79. Tobias-Machado M, Gomes DC, Faria EF, Zampolli HC. Robotic parastomal hernia repair. Int Braz J Urol. 2021;47(2):468-9. doi: 10.1590/s1677-5538.Ibju.2020.0347


80. Frisanco Oliveira A, Tansini A, Toledo TR, Balceiro R, Onofre Vidal D, de Martino Lee ML, et al. Immunophenotypic characteristics of juvenile myelomonocytic leukaemia and their relation with the molecular subgroups of the disease. Br J Haematol. 2021;192(1):129-36. doi: 10.1111/bjh.17098


81. de Oliveira Klein M, Serrano SV, Santos-Neto Á, da Cruz C, Brunetti IA, Lebre D, et al. Detection of anti-cancer drugs and metabolites in the effluents from a large Brazilian cancer hospital and an evaluation of ecotoxicology. Environ Pollut. 2021;268(Pt A):115857. doi: 10.1016/j.envpol.2020.115857


82. Schiavetto CM, de Abreu PM, von Zeidler SV, de Jesus LM, Carvalho RS, Cirino MT, et al. Human Papillomavirus DNA Detection by Droplet Digital PCR in Formalin-Fixed Paraffin-Embedded Tumor Tissue from Oropharyngeal Squamous Cell Carcinoma Patients. Mol Diagn Ther. 2021;25(1):59-70. doi: 10.1007/s40291-020-00502-6


83. Leal LF, Szarek E, Berthon A, Nesterova M, Faucz FR, London E, et al. Pde8b haploinsufficiency in mice is associated with modest adrenal defects, impaired steroidogenesis, and male infertility, unaltered by concurrent PKA or Wnt activation. Mol Cell Endocrinol. 2021;522:111117. doi: 10.1016/j.mce.2020.111117


84. Ribeiro AG, Vermeulen R, Cardoso MRA, Latorre M, Hystad P, Downward GS, et al. Residential traffic exposure and lymphohematopoietic malignancies among children in the city of São Paulo, Brazil: An ecological study. Cancer Epidemiol. 2021;70:101859. doi: 10.1016/j.canep.2020.101859


85. Rodrigues VC, Soares JC, Soares AC, Braz DC, Melendez ME, Ribas LC, et al. Electrochemical and optical detection and machine learning applied to images of genosensors for diagnosis of prostate cancer with the biomarker PCA3. Talanta. 2021;222:121444. doi: 10.1016/j.talanta.2020.121444


86. Cita RF, Mendes MF, Nogueira DP, Souza TL, Stelet VN. The novel HLA-B*15:555 allele identified in a healthy Brazilian individual. Hla. 2021;97(1):73-4. doi: 10.1111/tan.14094


87. Cibula D, Dostalek L, Hillemanns P, Scambia G, Jarkovsky J, Persson J, et al. Completion of radical hysterectomy does not improve survival of patients with cervical cancer and intraoperatively detected lymph node involvement: ABRAX international retrospective cohort study. Eur J Cancer. 2021;143:88-100. doi: 10.1016/j.ejca.2020.10.037


88. Laubach JP, Schjesvold F, Mariz M, Dimopoulos MA, Lech-Maranda E, Spicka I, et al. Efficacy and safety of oral panobinostat plus subcutaneous bortezomib and oral dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma (PANORAMA 3): an open-label, randomised, phase 2 study. Lancet Oncol. 2021;22(1):142-54. doi: 10.1016/s1470-2045(20)30680-x


89. Buss LF, Levi JE, Longatto-Filho A, Cohen DD, Cury L, Martins TR, et al. Attendance for diagnostic colposcopy among high-risk human papillomavirus positive women in a Brazilian feasibility study. Int J Gynaecol Obstet. 2021;152(1):72-7. doi: 10.1002/ijgo.13362


90. De Marchi P, Leal LF, Duval da Silva V, da Silva ECA, Cordeiro de Lima VC, Reis RM. PD-L1 expression by Tumor Proportion Score (TPS) and Combined Positive Score (CPS) are similar in non-small cell lung cancer (NSCLC). J Clin Pathol. 2021. doi: 10.1136/jclinpath-2020-206832


91. Brunhara BB, Becker AP, Neder L, Gonçalves PG, de Oliveira C, Clara CA, et al. Evaluation of the prognostic potential of EGFL7 in pilocytic astrocytomas. Neuropathology. 2021;41(1):21-8. doi: 10.1111/neup.12698


92. Guimarães DP, Mantuan LA, de Oliveira MA, Junior RL, Costa AMD, Rossi S, et al. The Performance of Colorectal Cancer Screening in Brazil: The First Two Years of the Implementation Program in Barretos Cancer Hospital. Cancer Prev Res (Phila). 2021;14(2):241-52. doi: 10.1158/1940-6207.Capr-20-0179


93. de Oliveira-Junior I, Nahas EAP, Cherem AC, Nahas-Neto J, Vieira R. Sentinel Lymph Node Biopsy in T3 and T4b Breast Cancer Patients: Analysis in a Tertiary Cancer Hospital and Systematic Literature Review. Breast Care (Basel). 2021;16(1):27-35. doi: 10.1159/000504693


94. Carrara GFA, Evangelista AF, Scapulatempo-Neto C, Abrahão-Machado LF, Morini MA, Kerr LM, et al. Analysis of RPL37A, MTSS1, and HTRA1 expression as potential markers for pathologic complete response and survival. Breast Cancer. 2021;28(2):307-20. doi: 10.1007/s12282-020-01159-z


95. Longatto-Filho A, Fregnani JH, Mafra da Costa A, de Araujo-Souza PS, Scapulatempo-Neto C, Herbster S, et al. Evaluation of Elafin Immunohistochemical Expression as Marker of Cervical Cancer Severity. Acta Cytol. 2021;65(2):165-74. doi: 10.1159/000512010


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